涓縐嶅叿鏈塈NOS鎶戝埗浣滅敤鐨勪箤槌㈡簮媧繪ц偨
鐢寵鍙?CN202410038181.0
涓撳埄鍚嶇О:涓縐嶅叿鏈塈NOS鎶戝埗浣滅敤鐨勪箤槌㈡簮媧繪ц偨
鐢寵鏃ユ湡:2024-01-11
涓撳埄綾誨瀷:鍙戞槑鎺堟潈
鐢寵(鏉冨埄)浜?涓浗姘翠駭縐戝鐮旂┒闄㈠崡嫻鋒按浜х爺絀舵墍
鍙戞槑浜?闄堣儨鍐? 鐩告; 璺編鏄? 鑳℃檽; 榛勫崏; 鍚寸嚂鐕? 璧墊案寮? 鏉庢槬鐢? 鐜嬫偊榻? 鏉ㄥ皯鐜? 鐜嬭開
鍏紑(鍏憡)鍙?CN117820429B
鍏紑(鍏憡)鏃ユ湡:2024-06-18
鎽樿:鏈彂鏄庡叕寮浜嗕竴縐嶅叿鏈塈NOS鎶戝埗浣滅敤鐨勪箤槌㈡簮媧繪ц偨錛屽睘浜庣敓鐗╁尰鑽鍩熴傛墍榪頒箤槌㈡簮媧繪ц偨鍖呮嫭姘ㄥ熀閰稿簭鍒楀SEQ?ID?NO.32銆丼EQ?ID?NO.34鍜孲EQ?ID?NO.36涓殑鑷沖皯涓縐嶃傛湰鍙戞槑浠庝箤槌㈣倢鑲夐叾瑙g墿涓瓫閫夊緱鍒頒簡涓夌鍏鋒湁鏄庢樉INOS鎶戝埗媧繪х殑鑲斤紝榪欎笁縐嶈偨涓嶪NOS鐨勫鎺ヨ兘閲忓垎鍒負10.3kcal/mol銆?9.5kcal/mol鍜?9.8kcal/mol銆傞氳繃鐐庣棁緇嗚優妯″瀷錛屾祴瀹氬INOS铔嬬櫧琛ㄨ揪閲忕殑褰卞搷錛屼笁鏉℃椿鎬ц偨鍧囪兘澶熸姂鍒禝NOS铔嬬櫧鐨勮〃杈撅紝鏄疘NOS鐨勫鑲芥姂鍒跺墏錛屽茍鍏鋒湁寰堝ソ鐨勬姉鐐庢晥鏋滐紝涓庡凡鎶ュ埌鐨処NOS鎶戝埗鑲界浉姣斿叿鏈夋槑鏄劇殑浼樺娍錛屽彲鐢ㄤ簬棰勯槻鍙婃不鐤楃値鐥囷紝鍏鋒湁騫塊様鐨勫競鍦哄簲鐢ㄥ墠鏅?/p>